- He owns a cattle ranch in Tellico Plains, Tennessee.
- He is on the national advisory board for the National Association to Protect Children (http://www.protect.org) and lobbies on behalf of stronger penalties for crimes against children.
- His father, Lemuel Grady Keith Jr., was a personnel division worker for the Tennessee Valley Authority. His mother, Hilda Earle, was a worker for the Knox County Board of Education.
- He was college friends with Bill Bates, who played sixteen years for the Dallas Cowboys. He was seen on the sidelines of many Cowboys games during Bates's career.
- Has starred in two unrelated adaptations of Stephen King novels, both focusing on girls with supernatural powers: Firestarter (1984) and the television remake Carrie (2002).
- Not to be confused with actor Keith David.
- He has portrayed a sailor in the US Navy as a midshipman/naval aviation officer candidate, an enlisted man, and a commissioned officer.
- No relation to actor Brian Keith. When Brian Keith died a reporter walked up to David Keith and asked him about the passing of his father. Not realizing the reporter was mistaken, David ran out of the room and called his mother to find out what had happened.
- Born on exactly the same date as Stephen Furst (of St. Elsewhere (1982), National Lampoon's Animal House (1978), and Babylon 5 (1993) fame).
- Bears a strong resemblance to actor Robert Wuhl.
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