- Her second marriage, to Christian Holmes, heir to the Fleischmann Yeast fortune, ended in sensational headlines in 1931, when she claimed he kept her locked in a cage, and he charged her with marital infidelity.
- Suffered from diabetes in her later years, which resulted in having a leg amputated in 1954.
- Sister of actress Mary MacLaren.
- Great favourite of President Woodrow Wilson.
- Conducted a public feud with her actress-sister Mary MacLaren.
- Blonde, blue-eyed silent screen star of romantic melodramas in the 1920's, a former model. She was one of the first actresses to set up her own production company, 'Katherine MacDonald Pictures' (1919-1921). She was a significant box-office earner for First National and B.P. Schulberg, starring opposite Douglas Fairbanks, Thomas Meighan and William S. Hart. After her retirement from acting, she ran a cosmetics business.
- In 1922, the New York Daily News, in a week-long promotion, declared her "the most beautiful woman in the world.".
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