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1-85 of 85
- Joel and Zach help an army man in the field. Charlie and Dawn try to save a hand while Maggie and a really pregnant Alex take their board exams.
- Dawn diagnoses Alex with an irregular heartbeat. The Great Randall returns to Hope Zion Hospital after an experimental cancer treatment goes wrong. Meanwhile, Charlie struggles with the implications of his fight with Joel, who is trying to treat a troubled mathematician. One of Hope Zion's staff is attacked and their life is left hanging in the balance.
- When a bomb goes off at a local charity run, Hope Zion Hospital receives the majority of the casualties, including some of its own doctors.
- When an ice storm strikes the city on Christmas Eve, Alex and Dawn struggle to keep a good Samaritan alive long enough for her family to say goodbye.
- While planning her mother's memorial service, Alex treats a young chronic kidney patient who has a "savior sibling" who is going to donate one of her kidneys, but when she presents with a cardiac virus, the sick sister becomes the savior. Meanwhile, Maggie and Sydney rediscover and rekindle their relationship while treating an interesting young couple.
- Alex and Shahir operate on a patient who drilled his own head. Maggie suspects Dana's daughter is stealing painkillers. Meanwhile, Joel sleeps with Selena.
- In aftermath of the disaster, Alex struggles with the fact she unknowingly helped the bomber at the expense of a friend.
- When a chef with oral cancer refuses care to pursue his life's work, Alex must confront her own feelings about the way Dana is handling her treatment.
- The time has come for Charlie to undergo surgery.
- When a John Doe comes into the hospital after being struck by a subway train, it's a race against the clock to save his life, but things take a more dramatic turn when Charlie realizes that the man is no John Doe, but "The Great" Randall Crane. Maggie attempts to leave her past behind, but that proves impossible when Sydney Katz comes back to town, urging Maggie to put her pregnant sister in the now-defunct cancer study. Away from the hospital, Alex takes her mother to their family farm in the wake of Martha's diagnosis, only to find out that Martha wants to take her own life before her illness gets the chance.
- The doctors are forced to deal with people from their past as Alex, Charlie, and Joel take on the daunting task of operating on a malpractice lawyer known for suing every doctor in his path.
- With her body still in a coma, Alex shares an emotional journey with Charlie in the spirit world as he 'ghost-doctors' a brain-dead mother-to-be. Meanwhile, Joel forms a tight bond with a lively drug addict while trying to treat his necrotic leg. Hope Zion Hospital also welcomes its new OB/GYN, Dr. Sydney Katz, who throws Maggie off her game.
- During a lunar event, Alex asks Joel and Maggie for help on a patient with contradicting symptoms. Charlie encounters a patient who believes she is dead, and Zachary's son pays him a visit.
- When Alex's brother Luke is admitted to Hope Zion Hospital in critical condition, Joel and Charlie must work together to keep him alive while keeping his admittance a secret from Alex. Meanwhile, Alex figures out a way to remove a tumour from a patient pregnant with twins, while Maggie is thrown off her game by the patient's gorgeous OB/GYN.
- Alex has been tricked into a blind double date and ends up rushing her mystery man to the ER. Charlie struggles with a spirit in the middle of a soldier's life-or-death surgery.
- After being stabbed in the heart, Alex has a profound experience in the liminal space, while a desperate Charlie and Dawn race against the clock to save her life. Meanwhile, Joel is pulled in to the ER to treat a suicidal patient that tests his duty as a doctor, and Maggie makes a bold decision that changes her relationship with Gavin.
- A motocross rider is diagnosed with Leukemia, forcing Alex to navigate family secrets in order to put her patient on the road to recovery.
- Alex and Shahir bring Charlie to the O.R. for a last resort procedure, but Charlie must first face his past before he can wake up. Meanwhile, Joel performs a risky surgery on a female jockey and Gavin crosses the line when he meets an Alzheimer's patient.
- Charlie returns to Hope Zion for his first shift as a doctor since waking from the coma and is surprised that he can still see the spirits of people who died at the hospital.
- While struggling under the pressure of deciding on her specialty, Alex is inspired by an immigrant doctor who needs her help to save his wife.
- When Alex and Joel end up stranded in the middle of nowhere with a severely injured couple, they're forced to use only what's around them to stabilize the pair until paramedics arrive. Meanwhile, back at Hope Zion Hospital, Charlie must try to save the wounded leg of his former college roommate as Gavin attempts to help Shahir improve his bedside manner.
- Alex is awake but still not back to her old self, and Dawn has given strict orders for her recovery plan. Meanwhile, Charlie and Joel square-off over differing treatment options when two fused-together burn victims are brought into the ER. Maggie finds herself in a whirlwind of emotions triggered from the fallout of her miscarriage.
- When the life of one of the doctors at Hope Zion Hospital is at risk, Alex has to put her personal and professional issues aside. Charlie has to deal with the ghost of a ballerina.
- As Alex leaves Hope Zion she becomes a witness to an accident that brings her back to the hospital.
- A dark day for one couple becomes a beacon of hope for others when a rare kidney sets off a transplant chain. The doctors of Hope Zion work to ensure that complications are avoided. In the ward, Dr. Charlie Harris treats the couple but needs the help of Kristine, when the woman's spirit takes to roaming the halls. Meanwhile, Dr. Dana Kinney endures the company of a chatty Poetry Professor, during a chemo session.
- Alex's new patient is someone from her past. Zach deals with a female patient that feels responsible for her friend's death. Charlie helps his new ghost cope with her current situation. Charlie finally figures out the truth about Crenshaw.
- Alex and Jeremy struggle to find the truth when all the symptoms of a permanently ill child point towards his mother as the cause.
- In an attempt to see what his life would be like without his gift, Charlie struggles to heal a superstitious farmer without the help of his spirit Intel.
- Alex teams up with Cassie to free a young woman from her abusive partner, while Dawn faces a series of life-threatening complications when a patient's pacemaker malfunctions.
- Nurse Kristine suffers a heart attack. Charlie helps her find out why she is not crossing over. A tough surgery affects Maggie's pitch. A misunderstanding develops between Dawn and Zach while romance blossoms between Jeremy and Cassie.
- It's a not-so-Happy Birthday for Alex, who's still reeling from her split with Charlie. To make matters worse, she makes a promise to a young girl, whose own birthday is derailed by her father's sickle cell crisis. Charlie treats a paranormal skeptic, only to discover this supernatural naysayer has a haunting of his own. And Cassie confronts her inner fear of parasites with some exposure therapy, as she treats a brother/sister duo riddled with every infestation.
- Alex and Maggie work together to deliver a baby; Charlie treats a magician.
- When a plane is forced to land due to a sick passenger, the patient is taken to Hope Zion where Alex performs emergency surgery and discovers that this passenger may have brought a deadly and contagious virus into the hospital.
- After a major turn of events, Alex is faced with a monumental question: is her life now changed forever? Meanwhile, Joel is in a race against time to save a young patient from rapidly advancing flesh-eating disease.
- After a young, healthy, and hunky fireman dies suddenly at a Hope Zion Hospital fundraiser, Alex must take the stand at Hope Zion's Morbidity and Mortality (M&M) Rounds to find out what went wrong and who is to blame. Meanwhile, Charlie and Zack deal with a nervous aspiring nun with an ankle fracture that turns serious when they stumble upon a potentially fatal allergy. A busy Joel struggles to balance his workload as Chief with his growing commitment to Sonja, and must decide if he's ready to step up to the plate.
- Victims of a car accident, a mother and her son arrive at the hospital. Alex and Joel discover that the mother needs a transplant. The spirit of the mother wants Charlie to console her son.
- The relationship between Alex and Joel is tested by a marathon surgery session involving an injured race-car driver. Meanwhile, Charlie has an eventful day off and a hospital "frequent flyer" keeps a number of doctors hopping.
- Alex risks a dangerous surgery on a seemingly inoperable tumor to save a young boy's life. Meanwhile, Joel struggles with the challenges of being Chief of Surgery as Charlie struggles with the spirit of Alex's dead brother Luke.
- A couple is attacked by a bear, but Alex and Charlie think there's more to the story.
- Alex races to find an organ replacement, while Charlie is pushed to his breaking point.
- Joel's father visits. Alex and Maggie deal with a patient who refuses Sydney's help with her baby. Charlie helps a young soul find his body.
- Joel waits for a call from his lawyer on whether or not he goes to trial. Alex tries to save a boy who was crushed by a tree. And Zach thinks he might have prostate cancer.
- Alex and Dana work to save the life of a single mother who is used to calling the shots in her daughters' lives.
- Alex wrangles the team in a high bid effort to diagnose the mysterious illness that haunts a beloved English teacher.
- Alex must decide whether or not to use information Charlie gets from a patient's spirit in order to save their life.
- Alex learns to stand up to Charlie's ex-wife Dawn.
- Alex must become the unlikely advocate for a violent young prisoner brought in to Hope Zion Hospital, while Joel connects with a disfigured refugee and tries to convince Dr. Dana Kinney to come back to operate on him. Meanwhile, a spirit who is familiar to many Hope Zion doctors shows up in the morgue when Charlie is about to do a routine procedure.
- Alex returns to work and meets a new colleague. Meanwhile, Joel gets involved in a dangerous situation at a local clinic and Gavin has a blissful experience.
- Alex gets caught between Dana and her daughter. Dawn and Melanda deal with a patient who intends to sue the hospital for malpractice. Charlie encounters an MMA patient and her rival.
- While searching for Charlie, Alex finds a caterer who was caught in the crossfire; Grace's mother asks for a priest; Dana consults with Cassie about a male stripper.
- Alex and Maggie deal with a tough lawyer after surgical complications with their patient.
- Charlie and Manny go toe-to-toe while treating two star-crossed lovers who are having an affair. Maggie and Dawn's different approaches to medicine are put at odds while treating a dad with a ninja star injury and his worried young son, while Dawn also deals with her bid to get back the Chief of Surgery position, and Maggie evaluates the residents.
- Alex and Charlie change their wedding plans; Zach takes a special interest in a case; a coma patient wake up with no memory.
- With Charlie removed from his ventilator, all he and Alex can do is wait and ask themselves: is this really it? But when a patient comes in for a routine follow-up, her new symptoms could lead Alex and Charlie to making a discovery about Charlie's coma. Meanwhile, Joel cannot operate after breaking his hand, and Maggie and Gavin deal with the aftermath of their kiss.
- When a severely injured man under the spell of hypnosis cannot remember his identity, the hypnotist who put him under is called into the hospital - where he uses his psychic ability to connect Charlie and Alex. Meanwhile, a young woman comes into the E.R. with a neck injury, but it's Hope Zee's psych resident, Gavin who knows how to help her.
- When a heat wave hits the city, Alex is appointed Trauma Team Leader as the hospital is faced with an influx of patients during a blackout. With no back-up power available, Dawn and Charlie must figure out a way to continue their surgery as Joel and Maggie attempt to keep a patient alive while stuck in an elevator.
- Alex struggles to help an older woman who starts to believe the year is 1985. Meanwhile, Charlie and Joel are pitted against one another by two best friends with identical shoulder injuries.
- Alex and Charlie find themselves working side by side to save the life of a man on the run.
- Alex is back to work where she meets meticulous doctor, Patrick Curtis, with whom she argues. Zach puts his life in danger for the sake of his patient. Charlie takes an important decision regarding his family life.
- When an aggressive brain tumor threatens the life of her patient, Alex must convince Shahir to use an equally aggressive treatment.
- While Charlie tries to save the life of a young man he is haunted by a mischievous spirit.
- With Charlie's life hanging in the balance, Alex and Dawn go head-to-head over who gets to be his legal decision maker - but are forced to put personal matters aside when they scrub into a heart transplant surgery together. Charlie, meanwhile, is in no mood to talk to the heart donor - a deceased prisoner.
- When Joel gets cold feet in the OR, Kinney takes him with her on a Continuing Medical Education assignment in her hometown to help clear his head. During their field trip, a woman gets pinned underneath a truck and Joel and Kinney lead the rescue effort. Meanwhile, Charlie meets a newly deceased therapist who suspects it's an emotional block that is keeping him in his coma. Encouraged by Charlie breathing on his own, Alex continues her rounds and diagnoses a fitness buff with a rare condition.
- When Alex is forced to put a patient's gender reassignment surgery on hold, she discovers a secret in his medical history that could save his surgery, but tear his life apart. Charlie deals with a patient who is healthy, sane - and convinced she is going to die at midnight. Meanwhile, Joel secretly helps Sonja deal with a patient of hers who's been admitted to Hope Zion Hospital.
- Alex and Charlie team up on a teenage girl's double surgery; Joel spends a day at a clinic and joins in a search-and-rescue mission in a ravine. Meanwhile, Maggie gets on Dr. Katz's bad side.
- News of Alex's pregnancy and the mystery of who the father is circles the hospital. Joel returns after his quick incarceration. Maggie studies for the board exam and deals with a patient who has a fear of doctors. Meanwhile, Alex and Dawn continue to deal with their patients in need of a heart donor.
- Charlie is assisted by the prisoner coma patient Crenshaw in dealing with a patient. Maggie tries to decide whether or not to leave Hope Zion and move on with her career. Alex directly questions the judgment of a senior surgeon in the OR.
- Patrick and Shahir give a patient contradictory advice about love. Alex is assisted in a surgery by a new resident. Maggie is preparing to leave Hope Zion when she receives an unexpected phone call. Zach has a dispute with a patient that works for the hospital.
- Alex must maintain her professionalism when Kristine shows up at Hope Zion Hospital after a drunk-driving accident with baby Luke's blanket.
- Alex tracks down the father of a patient who needs a liver transplant; the new CEO of Hope Zion is at odds with Dawn; Zach faces trials in the E.R.
- The board questions the hospital staff about Charlie's behavior; A patient convinces Alex to use new-age techniques; Shahir agrees to do an in-utero surgery.
- Dr. Hamza and Dr. Reid try to save the memory of a young woman suffering from Alzheimer's with a radical surgery.
- Alex tries to help a patient who hurt himself while breaking into a house; a friend of Dev's has been beaten by the police; A heart patient wishes to open an animal sanctuary.
- Alex treats a young boy with mysterious symptoms while dealing with the arrival of Charlie's ex-wife. Elsewhere in the hospital, Joel and Maggie try to help a patient who refuses life-saving treatment on religious grounds.
- A high profile double hand replantation becomes Alex's chance to prove to Kinney that she is still capable of being Chief Surgical Resident. In the ICU, Maggie believes a homeless man may have been misdiagnosed.
- A sleep-deprived Alex takes on a night shift in the ER where an all-star hockey enforcer may be skating full-speed towards an early death. Meanwhile, Charlie meets a suburban punk who is facing the biggest fight of his life.
- A routine surgical procedure goes awry when Alex's patient, a soon-to-be-wed young woman, falls into a coma. While Alex struggles with a case that hits close to home, Joel treats a patient who does his own body modifications, and Charlie finds himself drawn to Alex's coma patient in the spirit world.
- 2012–201743mTV-147.5 (60)TV EpisodeAlex treats a meditation instructor who wants to be awake in surgery. Cassie treats a hyped-up professional wrestler. Charlie walks out of an operation on a man he met earlier on the road. His psychiatrist shows him that he's confusing ghosts for the living.
- Alex has to put her concerns for Charlie aside when a chance to perform a cancer surgery arises.
- After Charlie's hand moved in the last episode, Alex has high hopes for his recovery, while she treats a patient who already has multiple surgeries under his belt. Meanwhile, Charlie coaches a young man killed in a roofing accident who has unfinished business with his severely injured brother.
- Tempers flare as Dev's med school rival, Billy Scott arrives at Hope Zion, while Alex breaks the rules and puts her job in jeopardy to help Manny save the life of an at-risk youth, and Charlie and Maggie treat an 1812 War re-enactor, whose complications align with the historical character he's playing.
- Alex's alarm at home goes off; Alex and Maggie ask Charlie for his opinion on a patient's treatment.
- When Hope Zion Hospital's Chief of Surgery ends up in a coma, he finds himself wandering the halls in spirit form. Stuck between worlds, he watches as his fiancée and the staff of the hospital fight to keep patients - and hope - alive.
- Alex and Maggie discover that one of the car crash survivors they're treating has breast cancer, and is a match for their cancer study. Meanwhile, Dana's resolve to re-certify in Trauma is tested when Dawn pushes her to treat a mangled motorcyclist, and Charlie is pulled into surgery before his arm is completely healed.
- On the way to their honeymoon, Alex and Charlie are called to the scene of a bus accident. Their wedding night is abruptly derailed by some traumatic déjà vu.