Paul Brinegar, Steve Raines , Charles H. Gray and Rocky Shahan all went on to co-star in the TV series Rawhide (1959).
Composer Paul Sawtell re-uses his theme music from The Cariboo Trail (1950) for the start of the cattle drive as Gloria Talbott is counting the cattle.
In this film, Paul Brinegar plays Gloria Talbott's grandfather, even though he was only 14 years older than she. Eight years later in The Case of the Unwelcome Well (1966), they would be cast as husband and wife.
In Rawhide (1959) Paul Brinegar's full character name was George Washington Wishbone. His brother, who showed up in the episode Incident of the Tinker's Dam (1960) was played by Regis Toomey. His character was named Thomas Jefferson Wishbone. In "Cattle Empire" Brinegar is Thomas Jefferson, but his brother, George Washington, is played by another actor.