Kristin Kreuk (Laurel Yeung) was a regular cast member on both Edgemont (2000) and Smallville (2001) simultaneously from 2001 to 2005.
Dominic Zamprogna (Mark Deosdade), Sarah Lind (Jennifer 'Jen' MacMahon) and Vanessa King (Anika Nedeau) are the only actors to all 70 episodes of the series.
Grace Park (Shannon Ng) was a regular cast member on both Edgemont (2000) and Battlestar Galactica (2004) simultaneously from 2004 to 2005.
Shortly after the filming of the first season was completed, Myles Ferguson (Scott Linton) was killed in a car accident on September 29, 2000 at the age of 19. Scott's absence from Season Two onwards is not explained.