- Dr. Meredith Grey: [voiceover] Okay. Anyone who says you can sleep when you die... Tell them to come talk to me after a few months as an intern. Of course it's not just the job that keeps us up all night. I mean if life's so hard already, why do we bring so much trouble on ourselves. What's up with the need to hit the self-destruct button? Maybe we like the pain. Maybe we're wired that way because without it... I don't know. Maybe we just wouldn't feel real. What's that saying... Why do I keep hitting myself with a hammer? Because it feels so good when I stop.
- Dr. George O'Malley: How's a pompous cocky jackass like you always have women all over him?
- Dr. Alex Karev: Little bluebell pills. Lots of them.
- Dr. George O'Malley: Oh c'mon.
- Dr. Alex Karev: Float like a butterfly sting like a bee. O'Malley, you think too much, can't you see it? You gotta dance and jab, dance and jab! Like me. I am the Ali of this place.
- Dr. George O'Malley: Yang. I'm scrubbing in on a hemospherectomy with Shepherd.
- Dr. Cristina Yang: Get out! I would kill for that.
- Dr. George O'Malley: We're cutting out half the girl's brain, and it's going to work. It's outrageous. Almost makes it kinda hard to hate him.
- Dr. Cristina Yang: Why do you hate him?
- Dr. George O'Malley: Oh, no reason.
- Dr. Cristina Yang: Oh, you know about him and Meredith?
- Dr. George O'Malley: You know?
- Dr. Cristina Yang: When are you gonna figure out that I know everything?
- Dr. George O'Malley: [to Izzie who is walking up the stairs] She knows.
- Dr. Isobel 'Izzie' Stevens: Oh, about doctor-cest?
- Dr. Cristina Yang: It's been going on for, like, ever.
- Dr. Isobel 'Izzie' Stevens: Seriously?
- Dr. George O'Malley: And you didn't tell us?
- Dr. Cristina Yang: And you didn't tell us?
- Dr. George O'Malley: I am not!
- Dr. Isobel 'Izzie' Stevens: I am!
- Dr. George O'Malley: He's about to go into major brain surgery on no sleep? That's not very responsible.
- Dr. Cristina Yang: Jealous? Sex all night isn't about being reponsible.
- Dr. Isobel 'Izzie' Stevens: No, it's about sex all night. I can't believe you're not pissed off about this, you of all people.
- Dr. Cristina Yang: Well, she works hard all day. She's good at her job, why should you care how she unwinds? I mean you like to bake all night, others like to drink, others like an occasional screaming orgasm.
- Dr. Alex Karev: [walking up] Yeah we do.
- Dr. Meredith Grey: [to Claire] You don't know this yet, but life isn't supposed to be like this. It's not supposed to be this hard.
- Dr. Meredith Grey: Okay, anyone who says you can sleep when you die, tell them to come talk to me after a few months as an intern. Of course, it's not just the job that keeps us up all night.
- Dr. Meredith Grey: I tried to talk Dr Shepherd out of that clot surgery. What is wrong with me?
- Dr. Alex Karev: Basically, you tried to kill a guy.
- Dr. Cristina Yang: [to Alex] Basically, you're an ass
- Dr. George O'Malley: Hey, have you seen Shepherd?
- Dr. Isobel 'Izzie' Stevens: Not as up close as Meredith has.
- Dr. George O'Malley: Hey, are you trying to get her in trouble? She's our friend.
- Dr. Isobel 'Izzie' Stevens: George, this program will make or break our careers, some of us will make it through and some of us won't. And that decision depends entirely on recommendations from doctors like Shepherd. There is a reason we don't sleep with the attendings.
- Dr. George O'Malley: It's not her fault, it's Shepherd's. He's an attending; he should know better. He's taking advantage of her.
- Dr. Isobel 'Izzie' Stevens: It didn't exactly sound like anything was happening against her will last night.
- Dr. Isobel 'Izzie' Stevens: If you wait a few minutes, you can have a piece of cake. Baked choc full of love. Actually, choc full of unrelenting, all-consuming rage and hostility, but still tasty.
- Dr. George O'Malley: You get any sleep?
- Dr. Isobel 'Izzie' Stevens: She should oil the bedsprings, as a courtesy, or at least buy a padded headboard.
- Dr. George O'Malley: So, who's the guy?
- Dr. Isobel 'Izzie' Stevens: You think it was just one guy doing all that work?
- Dr. George O'Malley: Do you mind if I don't think about that?
- Dr. Isobel 'Izzie' Stevens: Oh, you jealous?
- Dr. George O'Malley: I'm not jealous.
- Dr. Isobel 'Izzie' Stevens: Well, I am. Least I know she'll be having a long day at work.
- [They see Derek leave]
- Dr. Isobel 'Izzie' Stevens: Well, at least we know brain surgery isn't his only skill.
- Dr. Preston Burke: [taking the X-ray and showing it to Bailey walking by] You remember this guy?
- Dr. Miranda Bailey: Ay, the tattooed masochist
- Dr. Preston Burke: Had himself shot again
- Dr. Miranda Bailey: Glad to see he's still stupid