Cameron Richardson, the actress who played the 15-year-old supermodel patient, was 26 at the time this episode aired.
The first time we see House's damaged thigh.
Jennifer Morrison, the actress playing Dr. Cameron, and Cameron Richardson, the actress playing the patient, Alex, were the same age at the time of filming. They were both born in 1979 and were 27 years old in this episode despite one of them playing a 15 year old child and the other playing a doctor in her late 20s.
Couvade syndrome (sympathetic pregnancy) is a documented condition; however, it is not officially recognized by the American Medical Association and many other medical associations. The cause of the condition is highly debated; some physicians think it's psychological while others believe there is a physical explanation. Some studies have shown that men experiencing sympathetic pregnancy have elevated levels of cortisol and estrogen and lower than normal testosterone levels.
Naltrexone is a long-acting opioid antagonist, similar in function to naloxone (Narcan). The primary differences are that naloxone takes effect very quickly (one minute if given intravenously and five minutes intramuscularly) and it's short-acting; its effects only last about 90 minutes, which is why it helps reverse acute opioid overdoses. Naltrexone is mainly used to help detox from opioids because it has a longer onset of action; when given intravenously, it takes at least 30 minutes to start to work, and it stays in the system for up to 12 hours. Detox can be done in as little as two hours under general anesthesia (known as an "ultra-rapid detox"), though this is rarely done as it can be very dangerous. "Rapid detox" is done over a day while the patient is sedated to minimize discomfort, this route being a safer option. A "standard detox" is done over multiple days in inpatient rehab--naltrexone is administered orally, and the patient is given other medications to reduce withdrawal symptoms; this is the most common method of detoxing with naltrexone. After a patient has detoxed, they are often given monthly injections of naltrexone to help them stay sober; if they relapse and use opioids, the naltrexone will block their effects.