Detectives Eames' surrogate pregnancy was written into the storyline because actress Kathryn Erbe was pregnant with her second child.
While in the house with all the "original Laurette furniture," one of the pieces is actually an Eames chair. At one point, Detective Eames stands right next to it.
The title of this episode is a Shakespearian reference, describing the ambitious Lady Macbeth, who ruthlessly plots the death of a man visiting her home: "Bring forth men-children only; / For thy undaunted mettle should compose / Nothing but males" (Macbeth, Act I, Scene 7).
Alexandra Eames says, "What did Meredith know and when did she know it?" That is a paraphrase of Sen. Howard Baker's (R-TN) famous 1973 question about President Richard Nixon's involvement in the Watergate scandal, "What did the President know and when did he know it?"