Although listed in the end credits, regular characters Mr. Quizzer and Goldie Fisher do not appear in this episode. Mr. Quizzer actor Kevin Fleming reprises his recurring characters of Bill's Dad, Felton Fanboy, and Det. Abouttoretire, and Goldie Fisher actress Leila Gorstein reprises her recurring characters of Bill's Mom and Det. Newtotheforce, and debuts a new character - Felicia Fangirl.
With Bill feeling under the weather in this episode, the guest cartoon curators are Kerwyn (the prehistoric rubber chicken from Svengoolie (1995)), Bill's Mom and Bill's Dad, Felton Fanboy ("Pop-Culture Fanatic") and Felicia Fangirl ("Another Pop Culture Fanatic"), and MeTV cops Det. Abouttoretire and Det. Newtotheforce.
MeTV's resident horror host Svengoolie pays a visit from his Sven Manor music room, sending Bill a pouch containing home remedies that have been used by Sven's family for centuries. The remedies include an herbal tea bag made with wolfsbane (to take the sting out of a werewolf bite), a potion to relieve allergies to mummy dust (in refreshing lemon-lime flavor), and a sharpened wooden stick (an admittedly extreme "cure" for a vampire bite).