Joe Pesci was originally to portray Pete's paternal grandfather but was changed to his mother's father to preserve Pesci's Italian heritage.
Real-life friends of Pete playing themselves include John Mulaney, Machine Gun Kelly, Crillz, Derek, and Dave.
Stacy Keach narrates the opening disclaimer.
Pete's real life assistant Alex is the basis for the character Evan, and does appear in episode 6 in Pete's basement.
According to showrunner Judah Miller, other title ideas included "The Pete is On" "The Pete of the Moment" and "Can't Stand the Pete"