Although Aaron Ashmore is now listed as a regular, he will never appear on Artie's balcony during the opening credits.
The school that Hugo's nephew Brady goes to is the Tilson Academy. Gregg Tilson is listed in the credits as Co-Producer of this episode.
Claudia calls each of the cheerleaders Heather and tells them "not to have a brain tumor for breakfast". Those are both references to Heathers (1988)
Both Aaron Ashmore and Sam Huntington have played the Superman character "Jimmy Olsen". Sam in the movie Superman Returns (2006) and Aaron in the TV series Smallville (2001).
Brent Spiner and Saul Rubinek appeared together in the Star Trek: The Next Generation (1987). Saul Rubinek played an alien named Kiva Fajo who kept Data prisoner for his toy collection. The episode also stars Rene Auberjonois who played Odo on Star Trek: Deepspace 9.