- History of Everything(uncredited)Written by Barenaked LadiesPerformed by Barenaked Ladies[Series theme song played during the opening titles]
- Buffy the Vampire Slayer Theme(uncredited)Written by Nerf HerderPerformed by Nerf Herder[The music is playing when Leonard and Penny watch the show, then later when Penny and Bernadette watch the show]
- The Star Spangled Banner(uncredited)Music by John Stafford SmithLyrics by Francis Scott KeyPerformed by Mayim Bialik[Amy sings the song while accompanying herself on the keyboard]
- Pop Goes the Weasel(uncredited)Traditional[An instrumental version of the song is played on the toy music box]
- The Star Spangled Banner(uncredited)Music by John Stafford SmithLyrics by Francis Scott KeyPerformed by Jim Parsons[Sheldon sings the song to completion after Amy leaves the apartment]
- History of Everything (Instrumental version)(uncredited)Written by Barenaked LadiesPerformed by Barenaked Ladies[Instrumental version of series theme song played over the closing credits]
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