Filming was completed in 16 days.
The Kickstarter funded Spike Lee joint Da Sweet Blood of Jesus (2014) is a modern reinterpretation of Bill Gunn's cult classic blaxploitation film Ganja & Hess (1973).
According to cinematographer Daniel Patterson, 90 percent of the film was shot with two and sometimes three cameras rolling simultaneously.
Marks the first film appearance of Donna Dixon in 19 years. Dixon retired from acting with her last appearance in a feature film being Nixon (1995).
Is directly connected to Spike Lee's previous film Red Hook Summer (2012), being filmed in the same church with Thomas Jefferson Byrd reprising his role as "Deacon Zee" (here promoted to "Bishop Zee"), Stephen McKinley Henderson reprising his role as "Deacon Yancy," and Jon Batiste reprising his role as the church's organist TK Hazelton. [This also means this film is directly connected to Do the Right Thing (1989) as "Red Hook Summer" has Lee briefly reprising his role as Mookie the Pizza Boy.]