- James Clerk Maxwell(uncredited)Sung to the tune of "Bingo"Traditional nursery rhymePerformed by Jim Parsons[Sheldon sings the song to Leonard and Howard as the first rewritten nursery rhyme to get kids interested in science]
- Itsy Bitsy Spider(uncredited)With alternate lyricsTraditional nursery rhymePerformed by Jim Parsons[Sheldon sings the song to Leonard and Howard as the second rewritten nursery rhyme to get kids interested in science]
- History of Everything(uncredited)Written by Barenaked LadiesPerformed by Barenaked Ladies[Series theme song played during the opening titles]
- Eye of the Tiger(uncredited)With alternate lyricsWritten by Frankie Sullivan & Jim PeterikPerformed by Jim Parsons[Sheldon sings the song to Howard]
- History of Everything (Instrumental version)(uncredited)Written by Barenaked LadiesPerformed by Barenaked Ladies[Instrumental version of series theme song played over the closing credits]
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