- Jennifer Goines: Can't stop the plague. No, can't undo that.
- José Ramse: You know who started it?
- Jennifer Goines: Yes. No. There's only one who truly knows. Sees. Did see. Will see. The Witness.
- José Ramse: How do I find him?
- Jennifer Goines: Tell me where Cole is and I'll give you what you need.
- José Ramse: Cole's gone. I don't know where. How do you know what I need?
- [she produces an amulet]
- Jennifer Goines: Take it. It's yours. You're gonna need it later. You're a good friend. Not yet. But you will be.
- Dr. Julian Adler: What are you doing with those?
- José Ramse: Jones needs it.
- Dr. Julian Adler: She sent you?
- José Ramse: Yeah.
- Dr. Julian Adler: Are you lying to me, Mr. Ramse?
- José Ramse: [punches him] Yeah.
- James Cole: Look, I know this is hard for you to understand...
- Aaron Marker: No, I get it. The world is ending. You're a time traveler who doesn't know what he's doing.
- James Cole: Back off.
- Aaron Marker: You got her killed!
- James Cole: And then I got her back!
- Aaron Marker: Yeah, how many times're you gonna be able to do that? How many times does she have to die before you figure your shit out?
- [Cole stands up]
- Dr. Cassandra Railly: Cole.
- Aaron Marker: You don't know. Do you?
- Dr. Cassandra Railly: Stop it!
- Aaron Marker: You're right about one thing. The future's pretty bleak, if you're all they got.
- Dr. Cassandra Railly: Peters is recreating M5-10 for the 12 Monkeys, he'll need animals to test it on. The CDC can get a list of suppliers, and then I'll be able to track him down. Just like the Big Burn and the Night Room. Then splinter, apocalypse, rinse, repeat.
- Katarina Jones: Where's Ramse?
- James Cole: Tell me he won't get hurt.
- Katarina Jones: Why would that matter if you are successful?
- James Cole: Because getting Ramse killed can't be the last thing I do here.
- Katarina Jones: You know, anything we do, even if we undo it, it happened nonetheless, in God's eyes.
- Whitley: Sounds like Foster. You gettin' superstitious on me?
- Katarina Jones: I don't think that God's wrath requires my belief.
- Jennifer Goines: Not everything is preordained, no matter how it may seem. They say things happen for a reason. That is a lie.
- Dr. Cassandra Railly: [referring to Peters] It's too late to stop him from making the virus. That damage is done. I think that's enough.
- Aaron Marker: Okay. But he's not innocent.
- Dr. Cassandra Railly: He thought he was saving his husband. But he still made a choice.
- Aaron Marker: And I get it.
- Dr. Cassandra Railly: You do? Helping to destroy the world to save just one person?
- Aaron Marker: One person that you love. In the end, isn't that all that matters?
- Dr. Cassandra Railly: No.
- José Ramse: [before going back to the past] I promised my son I'd always protect him. I can't do it now. I'll do it then.
- [last lines]
- Katarina Jones: James. Mr. Ramse survives the jump, he's going to try and stop you.
- James Cole: And when he does, I'm gonna kill him.