Filmmaker Thomas Lilti is also a doctor and began to do short movies at the same time he studied medicine.
In this movie François Cluzet's character is facing a serious disease. In The Intouchables (2011), his character also deals with a serious health matter. Both films also have songs performed by Nina Simone on their soundtrack.
Stayed for 41 weeks in French theaters, the longest run for a 2016 French film.
While the film went through several working titles prior to release, "Irremplaçable" was the initial title of the script, the translation of which ended up being the International English title, Irreplaceable.
French visa # 138716.