Henry's recovery through anger from a mood modifying chemical, after which he deliberately takes on the much stronger Ray to bring Ray back, matches Captain Kirk's journey to provoke and take on Spock to cure him as well.
The title of this episode is the same name as Dr. Doofenshmirtz' evil organization in Phineas and Ferb, L.O.V.E.M.U.F.F.I.N. (League Of Villainous Evildoers Maniacally United For Frightening Investments in Naughtiness).