Lead characters Albert and Helen Hawks are played by real-life husband and wife Kevin and Nancy Butcher. The first two choices to play Helen Hawks had scheduling conflicts and production was close to being postponed. Though not a professional actress, Nancy Butcher was asked to play the part at the last minute, which added to the humorously authentic husband-and-wife banter.
Actor Josh Kreamelmeyer, who plays the Anesthesiologist, is a real-life nurse and provided many of the authentic props for the shoot from his own supply.
The Operating Room scene was filmed in a Nursing Lab at CollegeAmerica's Denver Campus where James Schuler used to teach Graphic Design.
The driver in the car scene was instructed to stay in the far right lane to contrast with Albert's smartphone's insistence that they turn left.
Nancy Butcher was not available for her driving scenes. Her 'stand-in' was a fifteen-year-old with a learner's permit. During takes, her mom laid in the back seat so that the driver's guardian would be "in the car" to keep the driving scene legal.